BrainDX

"»ç¶÷µéÀÌ ¿Ã¹Ù¸¥ Á¤º¸¸¦ ¾òÀ» ¶§ ¿Ã¹Ù¸¥ °áÁ¤À» ³»¸± °ÍÀÔ´Ï´Ù" - Thomas Jefferson

 

 

BrainDx, L.L.C.

BrainDX Normative Database

ºê·¹Àε𿢽º Ç¥ÁØ µ¥ÀÌÅͺ£À̽º

±â´ÉÀû ³ú ºÐ¼® º¸°í¼­ »ý¼º ½Ã½ºÅÛ

BrainDx´Â QEEG ºÐ¾ßÀÇ Ãʱ⠿¬±¸ÀÚ Áß ÀϺÎÀÇ ¿¬±¸¸¦ Æ÷ÇÔÇÕ´Ï´Ù. BrainDx´Â »ç°í¿Í ÇൿÀÇ ¹®Á¦¿Í °ü·ÃÀÌÀÖÀ» ¼ö ÀÖÀ¸¹Ç·Î ³ú ±â´É Àå¾ÖÀÇ Á¸À縦 Á¤ÀÇÇÏ´Â µ¥ µµ¿òÀ»ÁÝ´Ï´Ù. ÀÌ ½Ã½ºÅÛÀº ¸ðµç ¹®È­¿¡ °øÅëÀû ÀÎ ¸¹Àº ½Å°æ ¹× Çൿ Á¶°ÇÀÇ Ä¡·á¸¦ ÃÖÀûÈ­Çϱâ À§ÇØ Àü ¼¼°èÀûÀ¸·Î, Àú·ÅÇÑ ºñ¿ëÀ¸·Î ±×·¯ÇÑ Á¤º¸¸¦ ÀÌ¿ëÇÒ ¼ö ÀÖµµ·Ï ¼³°èµÇ¾ú½À´Ï´Ù.


BrainDx´Â Á¤·®Àû Àü±â »ý¸®ÇÐ ºÐ¾ßÀÇ ÁøÈ­¿¡¼­ ÆÄ»ý µÈ Áö½ÄÀ» ¿¬±¸½Ç¿¡¼­ ÀÓ»ó ½Ç½ÀÀ¸·Î ½±°Ô ¹ø¿ª ÇÒ ¼ö ÀÖµµ·ÏÇϱâ À§ÇØ ±¹Á¦ÀûÀ¸·Î ÀÎÁ¤ µÈ ½Å°æ »ý¸®ÇÐ ¿¬±¸ÀÚ ¹× ÀÓ»óÀÇ¿¡ ÀÇÇØ Çü¼ºµÇ¾ú½À´Ï´Ù. ÀÌ·¯ÇÑ ³ë·ÂÀÇ ÇÙ½ÉÀº ¿¬±¸ ¹× °³¹ß ´º¿å ´ëÇб³ ÀÇ°ú ´ëÇÐ Brain Research Laboratories¿¡¼­ ÀÌ ¿¬±¸ °á°ú´Â ±¹Á¦ÀûÀ¸·Î ¼ö¾øÀÌ ¸¹Àº Àü¹® »çȸ ȸÀÇ¿¡¼­ ¹ßÇ¥ µÇ¾úÀ¸¸ç Çй® ºÐ¾ß, ÇмúÁö, ±³°ú¼­ Àü¹Ý¿¡ ±¤¹üÀ§ÇÏ°Ô ±¤¹üÀ§ÇÏ°Ô ¹ßÇ¥µÇ¾úÀ¸¸ç ÀÇ·á, °èÃø, ±³À° ¹× ¹ýÀÇÇÐÀÇ ¿©·¯ ºÐ¾ß¿¡ Àû¿ëµÇ¾ú½À´Ï´Ù.


BrainDx´Â °í°´ÀÌ Á¤½Å Àå¾Ö ¹× ½Å°æ ÇÐÀû Á¶°Ç°ú °ü·ÃÇÏ¿© °³ÀÎÀ» ºÐ·ùÇÏ´Â µ¥ µµ¿òÀ̵Ǵ ¿©·¯ ¼öÁØÀÇ ºÐ¼®¿¡¼­ ³ú ±â´ÉÀ» Æò°¡ÇÒ ¼öÀÖ´Â ¸ðµâ ½Ã½ºÅÛÀ» °³¹ßÇß½À´Ï´Ù. 3 Â÷¿ø ±Ù¿ø ÇöÁöÈ­ ¹æ¹ýÀ» »ç¿ëÇÏ¿© ¼öÇÐÀûÀ¸·Î °¡Àå µÎµå·¯Áø ±âÃÊ ÀÚ·á ÀÎ µÎÇÇ ±â·Ï µ¥ÀÌÅ͸¦ ½Äº°ÇÏ¿© Àå¾ÖÀÇ º´Å »ý¸®ÇÐÀ» ´õ Àß ÀÌÇØÇÏ°í ÀǾàÇ°À» Æ÷ÇÔÇÑ Ä¡·á ±â¼úÀÇ ÃÖÀûÈ­ ¹× Æò°¡¸¦ µ½½À´Ï´Ù. BrainDx ±â¼úÀº ÀÓ»óÀÇ°¡ °³ÀÎÀÇ Çൿ ¹× ¼öÇà ´É·Â°ú °ü·ÃµÈ ½Å°æ ±â´É »óŸ¦ ¹®¼­È­ÇÏ´Â µ¥ »ç¿ëÇÒ ¼öÀÖ´Â Çؼ® º¸°í¼­¸¦ ÀÛ¼ºÇÕ´Ï´Ù.


º¸°í¼­ »ý¼º °úÁ¤ÀÇ ÀϺο¡´Â ȯÀÚÀÇ ³ú ±â´É ÇÁ·ÎÇÊ °á°ú¸¦ ³ªÀÌ°¡ ¸Â´Â Á¤»óÀÎ µ¥ÀÌÅͺ£À̽º¿Í ºñ±³ÇÏ´Â °úÁ¤ÀÌ Æ÷ÇԵ˴ϴÙ. ±×·± ´ÙÀ½ ȯÀÚÀÇ º´·Â Á¤º¸¸¦ ÅëÇÕÇÏ¿© °³º° ȯÀÚÀÇ QEEG ÇÁ·ÎÆÄÀÏÀ» ¾Ë·ÁÁø Àå¾Ö°¡Àִ ȯÀÚ¿Í ºñ±³ÇÏ´Â Åë°èÀû ºñ±³¸¦ ½Ç½ÃÇÏ°í ȯÀÚ°¡ Åë°èÀûÀ¸·Î ±×·¯ÇÑ È¯ÀÚ¿Í À¯»ç ÇÒ È®·üÀ» Æò°¡ÇÏ¿© Áø´Ü ÇÁ·Î¼¼½º¸¦ Áö¿øÇÕ´Ï´Ù. ¶ÇÇÑ, ÃÖÁ¾ »ç¿ëÀÚ°¡ Ä¡·á ¿É¼ÇÀÇ ¿ì¼± ¼øÀ§¸¦ Á¤ÇÏ´Â ÀÛ¾÷À» µ½±â À§ÇØ ÀÌ·¯ÇÑ ÇÁ·ÎÆÄÀÏÀ» ±â¹ÝÀ¸·Î Ä¡·á Àû °³ÀÔ¿¡ ´ëÇÑ ÀÓ»ó ÁöħÀ» Á¦°ø ÇÒ ¼ö ÀÖ½À´Ï´Ù.


¿¹¸¦ µé¾î, ȯÀÚ°¡ ±â¾ï »ó½Ç¿¡ ´ëÇÑ ÀϹÝÀûÀÎ ºÒ¸¸À» ³ªÅ¸³»°Å³ª ÀÚ½ÅÀÇ ¿¬±¸°¡ Àß ÁøÇàµÇÁö ¾Ê´Â´Ù°í ¸»Çϸé, BrainDx ½Ã½ºÅÛÀº ¿¬·ÉÀÌ ¿¹»óµÇ´Â Á¤»ó ¼öÄ¡¿Í ºñ±³ÇÏ¿© °´°üÀûÀ¸·Î ³ú ±â´ÉÀ» Æò°¡ÇÒ ¼ö ÀÖÀ¸¸ç, ÀÌ È¯ÀÚ´Â ÀÓ»ó ¿ì¿ïÁõÀÌÀִ ȯÀÚ°¡ ¾Æ´Ñ Ä¡¸Å ȯÀÚÀÇ È¯ÀÚ¿Í ÀÏÄ¡ÇÕ´Ï´Ù. ºñ ħ½ÀÀû ÀÎ 20-30 ºÐ QEEG ³ú Æò°¡´Â ƯÁ¤ Áõ»óÀ» °¡Áø ȯÀÚ°¡ ºñ½ÁÇÑ Áõ»ó°ú °´°üÀûÀÎ Áø´ÜÀ» °¡Áö°í µ¥ÀÌÅͺ£À̽º¿¡¼­ ´Ù¸¥ ȯÀÚ¿Í ÀÏÄ¡ ÇÒ È®·üÀ» Åë°èÀû Á¤È®¼º°ú ÇÔ²² »ý¼º ÇÒ ¼ö ÀÖ½À´Ï´Ù. ¿¹¸¦ µé¾î, ¼Ò¾Æ°ú ¹®Á¦ÀÇ °æ¿ì ÇнÀ Àå¾Ö (LD)¸¦ ÀÚÆóÁõ ½ºÆåÆ®·³ Àå¾Ö (ASD)¿¡¼­ Á¤»ó ¶Ç´Â ÁÖÀÇ·Â °áÇÌ / °úÀ× Àå¾Ö (ADHD)¿Í ±¸ºÐÇϽʽÿÀ. ,±âŸ. ¶ÇÇÑ BrainDx´Â ȯÀÚ°¡ µÎ °¡Áö »óÅ¿¡ÀÖÀ» ¶§ ³ú ±â´ÉÀ» Æò°¡ÇÒ ¼öÀÖ´Â ´É·ÂÀ» Á¦°øÇÕ´Ï´Ù. µÎ °¡Áö »óÅ »çÀÌÀÇ ³ú ±â´ÉÀÇ º¯È­¸¦ Á¤·®ÀûÀ¸·Î Æò°¡ÇÕ´Ï´Ù (¿¹ : ¾à¹° Åõ¿© ¹× Áß´Ü).


ÀÌ ¼ÒÇÁÆ®¿þ¾î µµ±¸´Â ´Ù¾çÇÑ Ç÷§Æû¿¡¼­ ÀÛµ¿Çϵµ·Ï Á¦°øµÇ¸ç Àü ¼¼°èÀÇ ¿¬±¸ ÇÁ·Î±×·¥À»À§ÇÑ µµ±¸»Ó¸¸ ¾Æ´Ï¶ó ´Ù¾çÇÑ ÀÓ»ó ¸ñÀûÀ» À§ÇØ ÇÕ¸®ÀûÀÎ °¡°ÝÀ¸·Î Á¦°øµË´Ï´Ù. ¸î ÃÊ ¸¸¿¡ EEG µ¥ÀÌÅÍ¿¡¼­ ã°íÀÖ´Â ´äº¯À» ¾ò°í ³ú - Çൿ °ü°è¿¡ °üÇÑ ´Ù¾çÇÑ Áú¹®À» Ž»öÇϽʽÿÀ.



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BrainDxÀÇ MissionÀº Æ÷°ýÀûÀÌ°í ½ÃÀÇ ÀûÀýÇϸç È¿À²ÀûÀÌ¸ç ºñ¿ë È¿À²ÀûÀÎ ¹æ½ÄÀ¸·Î Àü ¼¼°è ÀÇ·á Àü¹®°¡¿¡°Ô ÀÚµ¿È­ µÈ QEEG º¸°í¼­¸¦ Á¦°øÇÏ´Â °ÍÀÔ´Ï´Ù. BrainDx, L.L.C.ÀÇ ÆÄÆ®³ÊµéÀÇ ¹ÏÀ½ÀÔ´Ï´Ù. ´Â ȯÀÚÀÇ °Ë»ç·Î ¼öÁý µÈ ³úÆÄ µ¥ÀÌÅͷκÎÅÍ ÀǹÌÀÖ´Â Çؼ® º¸°í¼­ Á¦°ø¿¡ Çõ¸íÀ» ÀÏÀ¸Å³ ¼öÀÖ´Â ¹æ½ÄÀ¸·ÎÀÌ ¼­ºñ½º¸¦ Á¦°ø ÇÒ ¼öÀÖ´Â °íÀ¯ ÇÑ À§Ä¡¿¡ ÀÖ½À´Ï´Ù.


BrainD L.L.C. ¹ø¿ª ¿¬±¸¸¦À§ÇÑ ¸ðµ¨ÀÔ´Ï´Ù. ÀÌ ÇÁ·¹ÀÓ ¿öÅ©¿¡¼­ ½Ç¹«ÀÚ´Â ¹ø¿ª ½Ã½ºÅÛÀÌ ÀÀ¿ë ¿¬±¸º¸´Ù ¿ì¼öÇÑ °á°ú¸¦ ³¾ ¼ö ÀÖµµ·Ï ¾î·Á¿î ¹®Á¦¿¡ ´ëÇÑ ½ÇÁ¦ °ü·Ã ±âÁØÀ» Á¦°øÇÔÀ¸·Î½á ¿¬±¸ ÀÇÁ¦¸¦ ±¸Ã¼È­ ÇÒ ¼ö ÀÖ½À´Ï´Ù. ¹ø¿µÀ» À§ÇØ ¹ø¿ª ¿¬±¸¿¡´Â Áö½Ä ±â¹ÝÀÇ »ýÅ°谡 ÇÊ¿äÇÕ´Ï´Ù. Áö½Ä »ýÅ°è´Â ±¸¼º ¿ä¼Ò°¡ Á¶°æÀÇ ¸ðµç ºÎºÐ¿¡¼­ »ç¿ëÇÒ ¼öÀÖ´Â µ¥ÀÌÅ͸¦ »ý¼º, Á¦°ø, °ü¸® ¹× ºÐ¼®ÇÕ´Ï´Ù. ¸ñÇ¥´Â À¯¿ëÇÑ Áö½ÄÀ¸·Î µ¥ÀÌÅÍÀÇ º¯È¯À» °¡¼ÓÈ­ÇϱâÀ§ÇÑ Áö¼ÓÀûÀÎ Çǵå¹é ·çÇÁÀÔ´Ï´Ù. Çù¾÷, µ¥ÀÌÅÍ °øÀ¯, µ¥ÀÌÅÍ ÅëÇÕ ??¹× Ç¥ÁØÀº ¸Å¿ì Áß¿äÇÕ´Ï´Ù.


¹ø¿ª ¿¬±¸´Â Á¤º¸, µ¥ÀÌÅÍ°¡ º´¿ø, Áø·á¼Ò ¹× ¿¬±¸ Âü°¡ÀڷκÎÅÍ Ã¼°èÀûÀÌ°í ü°èÀûÀÎ Çü½ÄÀ¸·Î ÀúÀå¼Ò¿Í ½ÇÇè½Ç·Î È带 °ÍÀ» ¿ä±¸ÇÕ´Ï´Ù. ÀÌ µ¥ÀÌÅ͸¦ Áö¼ÓÀûÀ¸·Î ±¸Á¶È­ÇÏ°í ÅëÇÕÇÔÀ¸·Î½á NYUÀÇ Brain Research Laboratory (BRL)´Â ³ú °ü·Ã Àå¾ÖÀÇ º¹ÀâÇÏ°í ±Ùº»ÀûÀÎ ¿øÀÎÀ» Ž±¸ÇÕ´Ï´Ù. BrainDx´Â È¿°úÀûÀÎ ¿¹¹æ, Á¶±â ¹ß°ß ¹× ¸ÂÃã Ä¡·á¸¦ À§ÇØ °úÇÐÀÇ ÃÖ÷´Ü¿¡¼­ Áö½ÄÀÇ »ý»êÀû »ç¿ëÀ» ÃËÁøÇÏ´Â BRL°úÀÇ °ü°è¿¡ Á¾»çÀÚ¸¦ µ¥·Á¿É´Ï´Ù.



 

  • ºÐ¼® : ±Ô¹ü Á¢±Ù¹ý

    ¾î¸°ÀÌ ¹× ¼ºÀÎ ±Ô¹üÀº ÃâÆÇ µÈ ±â»ç¿¡¼­ ¼³¸íÇÑ °Í°ú µ¿ÀÏÇÑ ÀýÂ÷¸¦ µû¶ú½À´Ï´Ù. Ãʱâ Ç¥ÁØÀº Á¤ºÎ ÀÚ±Ý Áö¿ø (BEH, NSF, NIA)¿¡ µû¶ó ¼öÇàµÇ¾úÀ¸¸ç Æ÷ÇÔ / Á¦¿Ü ±âÁØ ¹× µ¥ÀÌÅÍ ¼öÁý¿¡ ´ëÇÑ ¾ö°ÝÇÑ ÇÁ·ÎÅäÄÝÀ» µû¶ú½À´Ï´Ù (ÀÚ¼¼ÇÑ ³»¿ëÀº °£Ç๰¿¡ ÀÖÀ½). ´ÙÀ½ »çÇ×À»ÁÖÀÇÇؾßÇÕ´Ï´Ù.
    ±Ô¹üÀº ȸ±Í ¹æÁ¤½ÄÀÌ ¹ÝÂÊ¿¡ Çü¼ºµÇ°í ´Ù¸¥ (µ¶¸³Àû ÀÎ º¹Á¦)¿¡¼­ Å×½ºÆ® µÈ ȸ±Í ¹æÁ¤½ÄÀ» »ç¿ëÇÏ¿© ±¸¼ºµÇ¾ú½À´Ï´Ù. ¿¹»óµÇ´Â "È÷Æ® ¼ö"(z °ª <0.05)º¸´Ù ÀûÀº °ªÀÌ ÈĹÝ. ±× ÈÄ µÎ °³ÀÇ ¹ÝÀ» °áÇÕÇÏ°í ÃÖÁ¾ ¹æÁ¤½ÄÀ» ±¸¼ºÇß´Ù. ´ë»óÀ» ´õ Ãß°¡ ÇÒ ¶§±îÁö ´ë»ó¿¡ ´ë»óÀ» Ãß°¡Çß´Ù (¿¬·É´ë¸¦ ³Ñ¾î) ȸ±Í ¹æÁ¤½ÄÀ» º¯°æÇÏÁö ¾Ê¾Ò´Ù. µû¶ó¼­ ±Ô¹üÈ­ µÉ ÇÊ¿ä°¡ÀÖ´Â Àα¸ÀÇ Å©±â´Â Åë°èÀûÀ¸·Î °áÁ¤µÇ¾ú´Ù. ±â´ëÇß´ø °Íº¸´Ù ´õ ¸¹Àº ¾î¸°À̵éÀÌ ¼ºÀκ¸´Ù ´õ »¡¸® (¿¬·É¿¡ µû¶ó ±Þ°ÝÇÑ º¯È­°¡ ÇÊ¿äÇÔ) ¿ä±¸µÇ¾ú½À´Ï´Ù.
    Ãß°¡ÀûÀÎ Æò°¡´Â ³ôÀº Å×½ºÆ® / Àç½ÃÇèÀÇ ¾ÈÁ¤¼º°ú Ç¥ÁØÀÇ ¾ÈÁ¤¼ºÀ» ÀÔÁõÇϱâ À§ÇØ »ç¿ëµÇ¾ú½À´Ï´Ù. Ãʱâ Ç¥ÁØÈ­ ÀÌÈÄ Ãß°¡·Î ¾î¸°ÀÌ ¹× ¼ºÀÎ Àα¸¿¡ ÁõÆø±â µîÀÇ ¹ßÀüÀ» ³ªÅ¸³»´Â ÁÖÁ¦°¡ Ãß°¡ µÈ Áö ¸î ³âÀÌ Áö³µ½À´Ï´Ù.
    ¸ðµç »õ·Î¿î ÇÇÇèÀÚ´Â Ãʱâ ÇÁ·ÎÁ§Æ®¿Í µ¿ÀÏÇÑ ±âÁØ¿¡ µû¶ó ¸ðÁýµÇ¾ú½À´Ï´Ù.


    ºÐ¼® : ·Î·¹Å¸ ±Ô¹ü

    LORETA (ÀúÇØ»óµµ ÀüÀڱ⠴ÜÃþ ÃÔ¿µ ºÐ¼®)´Â µÎÇÇ¿¡¼­ ±â·Ï µÈ Àü¾ÐÀÇ ¼öÇÐÀûÀ¸·Î °¡Àå °¡´É¼ºÀÌ ³ôÀº ¼Ò½º¸¦ ÇöÁöÈ­ÇϱâÀ§ÇÑ ¼Ò½º À§Ä¡ ÆÄ¾Ç ¿ª ¹®Á¦ ¹æ¹ýÀÔ´Ï´Ù. BRL¿¡¼­ Roberto Pascual-Marqui¿Í ÇÔ²² ÀÛ¾÷Çϸ鼭 º¹¼¿ Ç¥ÁØÀº µ¿ÀÏÇÑ BRL / NYU Ç¥ÁØ µ¥ÀÌÅͺ£À̽º¸¦ »ç¿ëÇÏ¿© °è»êµÇ¾ú½À´Ï´Ù Neurometrics¿¡ ¼³¸í µÈ ¹æ¹ý·ÐÀº sLORETA Ç¥ÁØ¿¡ Àû¿ëµÇ¾î ¸ðµ¨¿¡¼­ °¢ º¹¼¿ÀÇ z- º¯ÇüÀ» Çã¿ëÇÏ¿© ¼öÇÐÀûÀ¸·Î °¡Àå °¡´É¼ºÀÖ´Â ³ú º¸È£±âÀÇ ±âº» ¼Ò½ºÀÇ Åë°èÀû »ö»ó ÄÚµù À̹ÌÁö·Î Ç¥½Ã ÇÒ ¼ö ÀÖ½À´Ï´Ù. °¢ º¹¼¿¿¡ ´ëÇØ °³ÀÎÀÇ °ªÀº ¿¬·É¿¡ ´ëÇÑ ¿¹»ó Ç¥ÁØ°ú Åë°èÀûÀ¸·Î ºñ±³µË´Ï´Ù. °¢ º¸¼¿¿¡ ´ëÇÑ Åë°èÀû À¯ÀǼºÀº È®·ü ·ÐÀû MRI AtlasÀÇ Á¶°¢¿¡ °ãÃÄÁø »ö»óÀ¸·Î ÀÎÄÚµùµË´Ï´Ù. ±âÁ¸ÀÇ ½Å°æ ¿µ»ó ¹× EEG ¼Ò½º À§Ä¡ Æľǰú À¯»çÇÑ °á°ú¸¦ º¸¿©ÁÖ´Â ±¤¹üÀ§ÇÑ ¹®ÇåÀÌ Á¸ÀçÇÕ´Ï´Ù. °³¹ß µÈ ¿¬·É ȸ±Í ¹æÁ¤½ÄÀº ¾çÀû ³úÆÄ ÃøÁ¤À» Ç¥ÁØÈ­ÇÏ¿© ÇÇÇèÀÚ ¿¬·É°ú ¹«°üÇÏ°Ô Çؼ® µÉ ¼ö ÀÖµµ·Ï µµ¿ÍÁÝ´Ï´Ù. ¾Æ·¡ÀÇ sLORETA À̹ÌÁö´Â 16 ~ 80 ¼¼ (N = 154)ÀÇ ³ªÀÌ¿Í ÇÔ²² ´ë»ó°ú °ü·ÃµÈ »ó´ë ½Àµæ ȸ»ö ¹°Áú º¹¼¿ÀÇ »ó°ü °ü°è¸¦ ³ªÅ¸³»´Â ±×¸²ÀÔ´Ï´Ù. ȸ±Í´Â ³ªÀÌÀÇ ´ë¼ö¿Í ¼±Çü (Á÷¼± ÀûÇÕ)ÀÔ´Ï´Ù. °¢°¢ÀÇ ¾çÀº ȸ¹éÁú ¾çÀÇ 20 %¸¦ Â÷ÁöÇÑ´Ù. Àû»ö º¼·ýÀÇ ¸ðµç º¹¼¿Àº ÁÖÆļö 17.2Hz¿¡¼­ .48º¸´Ù Å« ³ªÀÌ¿Í ¾çÀÇ »ó°ü °ü°è°¡ ÀÖ½À´Ï´Ù. .58ÀÇ ÃÖ´ë °ªÀº ¿ÞÂÊ Insula¿¡ ÀÖ½À´Ï´Ù. û»ö ºÎÇÇÀÇ ¸ðµç º¹¼¿Àº 10.2 HzÀÇ ÁÖÆļö¿¡¼­ -44 ¹Ì¸¸ÀÇ »ó°ü °ü°è¸¦°¡Áý´Ï´Ù. ÀϹÝÀûÀ¸·Î ÀÌ°ÍÀº ÃøµÎ¿±ÀÇ º£Å¸°¡ Áõ°¡ÇÏ°í ³ªÀÌ°¡ Áõ°¡ÇÔ¿¡ µû¶ó ¾ËÆÄ°¡ °¨¼Ò ÇÔÀ» º¸¿©ÁÝ´Ï´Ù. °¢ º¹¼¿ÀÇ ÇöÀç ¹Ðµµ ÃßÁ¤Ä¡´Â ³úÆÄÀÇ ÃÑ ¿¡³ÊÁö·Î ³ª´²Áö°í (µû¶ó¼­ ÁÖ°üÀû »ó´ë °­µµ), µû¶ó¼­ÀÌ ÃøÁ¤¿¡¼­ ³úÆÄÀÇ Àüü Å©±âÀÇ ¿µÇâÀ» Á¦°ÅÇÕ´Ï´Ù.

    ±â´É °è»ê

    ±â´É °è»ê : Àü·Â ½ºÆåÆ®·³ ¹× ´ÙÀ½À» Æ÷ÇÔÇÑ °ü·Ã ±â´É :

    • Àý´ë ÆÄ¿ö Absolute power
    • »ó´ë ÆÄ¿ö Relative power
    • Æò±Õ ºóµµ Mean frequency
    • ¹Ý ±¸°£ ´ëĪ Intra- and Inter-hemispheric symmetry
    • ¹Ý ±¸°£ ÀÏ°ü¼º Intra- and Inter-hemispheric coherence


    ¼Ò½º ¿µ¿ªÈ­

    • LORETA °ü½É Áö¿ª (ROI)¿¡¼­ ÃøÁ¤.
    • Á¼Àº ÁÖÆļö ´ë¿ªÀÇ °æ¿ì,
    • precisley ½Ã°£ ÄÚµù À̺¥Æ®.
    * Ãß°¡ ºñ¼±Çü ±â´É¿¡´Â º¹À⼺ ¹× ¿¬°á¼º ÃøÁ¤ÀÌ Æ÷ÇԵ˴ϴÙ.


    °¢ ´ë¿ª Åë°ú¿¡ ´ëÇØ °è»ê µÊ

    • µ¨Å¸ (1.5-3.5Hz)
    • ¼¼Å¸ (3.5-7.5Hz)
    • ¾ËÆÄ (7.5-12.5Hz)
    • º£Å¸ (12.5-25Hz) ¹× º£Å¸ 2 (25-35Hz)
    * Ãß°¡ ºñ¼±Çü ±â´É¿¡´Â º¹À⼺ ¹× ¿¬°á¼º ÃøÁ¤ÀÌ Æ÷ÇԵ˴ϴÙ.


    Neurometrics¿¡¼­ »ç¿ëµÇ´Â ¹æ¹ý :

    • ±¹Á¦ 10/20 ¹èÄ¡ ½Ã½ºÅÛÀÇ 19 °³ Áö¿ª¿¡¼­ ¼öÁý µÈ µðÁöÅÐ EEG • 5000¥Ø ¹Ì¸¸ÀÇ ÀÓÇÇ´ø½º
    • ¸µÅ©µåÀ̾î·Î ÂüÁ¶ µÊ
    • ¹êµå Æнº = 0.5 ~ 50Hz, »ùÇà ¼Óµµ> = 100Hz
    • 20-30 ºÐ. EEG ±â·Ï
    • »óÅ = ´«°¨°í • ¾ÆƼÆÑÆ®°¡ ¾ø´Â 1-2ºÐÀÇ µ¥ÀÌÅÍ ¼±ÅÃ




BrainDX ¿¬±¸

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Âü°í¹®Çå (Bibliography)

½Å°æ °èÃøÇÐ( Neurometrics) ¹× ±Ô¹üÀÇ ¹è°æ ¹× ¿ª»ç

John ER, Karmel BZ, Corning WC, Easton P, Brown D, Ahn H, John M, Harmony T, Prichep LS, Toro A, Gerson I, Thatcher RW, Valdes P, Kaye H, Valdes P, Schwartz E. Neurometrics: Numerical taxonomy identifies different profiles of brain functions within groups of behaviorally similar people. Science 1977; 196: 1383-410.

John ER, Karmel BZ, Prichep LS, Ahn H, John M. Neurometrics applied to the quantitative electrophysiological measurement of organic brain dysfunction in children. In: Shagass C, ed. Psychopathology and Brain Dysfunction. Raven Press; 1977

John ER, Prichep LS, Ahn H, Easton P, Karmel BZ, Thatcher R, Toro A. Neurometrics: Quantitative electrophysiological measurement of organic brain dysfunction in children. In: Shagass C, ed. Psychopathology and Brain Dysfunction. Raven Press; 1977.

John ER, Karmel BZ, Corning, Easton P, Brown D, Ahn H, John M, Harmony T, Prichep LS, Toro A, Gerson I, Bartlett F, Thatcher R, Kaye H, Valdes-Sosa P, Schwartz E. Neurometrics: Computerized diagnosis and remediation of brain dysfunctions. In: Chacko GK, ed. Health Handbook. Amsterdam: N. Holland Publishing; 1979: 330-481.

Ahn H, Prichep LS, John ER, Baird H, Trepetin M, Kaye H. Developmental equations reflect brain dysfunction. Science 1980; 210: 1259-62.

John ER, Ahn H, Prichep LS, Trepetin M, Brown D, Kaye H.Developmental equations for the electroencephalogram.Science 1980; 210: 1255-8.

Ahn H, Prichep L, John ER. Electroencephalogram tests for brain dysfunction: A question of validity. Science 1982; 217: 82.

John ER, Prichep LS, Ahn H, Easton P, Fridman J, Kaye H. Neurometric evaluation of cognitive dysfunctions and neurological disorders in children. Progress in Neurobiology 1983; 21: 239-90.

Prichep LS, John ER.Neurometrics: Clinical Applications. In: Lopes Da Silva F, van Leeuwen WS, Remond A, eds. Handbook of Electroencephalography and Clinical Neurophysiology, Vol. 2. Amsterdam: Elsevier; 1986: 153-70.

John ER, Prichep LS, Easton P. Normative data banks and Neurometrics: Basic concepts, methods and results of norm construction. In: Gevins AS, Remond A, eds. Handbook of Electroencephalography and Clinical Neurophysiology, Vol. I. Amsterdam: Elsevier; 1987: 449-95.

Volkow ND, Gomez-Mont F, Inamdar M, Lamella M, Prichep L, John ER. Multivariate Analysis of the EEG in normal adolescents.Biol Psychiatry 1987; 22: 199-204.

John ER, Prichep LS. Principles of neurometrics and neurometric analysis of EEG and evoked potentials. In: Niedermeyer E, Lopes Da Silva F, eds. EEG: Basic Principles, Clinical Applications and Related Fields. Baltimore: Williams and Wilkins; 1993: 989-1003.

John ER, Zhang Z, Brodie JD, Prichep LS. Statistical probability mapping of brain function and structure. In: Thatcher RW, Hallett M, Zeffiro T, John ER, Huerta M, eds. Functional Neuroimaging: Technical Foundations. Academic Press; 1994: 137-43.

Hughes, J. R. & John, E. R. (1999). Conventional and quantitative electroencephalography in psychiatry. J Neuropsychiatry ClinNeurosci, 11, 190-208.

Koenig T, Prichep LS, Lehmann D, Valdes-Sosa P, Braeker E, Kleinlogel H, Isenhart R, John ER. Millisecond by Millisecond, Year by Year: Normative EEG Microstates and Developmental Stages.Neuroimage 2002; 16: 41-8.

John ER, Prichep LS, Friedman J, Easton P. Neurometrics: Computer-assisted differential diagnosis of brain dysfunctions. Science 1988; 293: 162-9.

Prichep LS. Use of normative databases and statistical methods in demonstrating clinical utility of QEEG: Importance and cautions. Clinical EEG 2005; 36: 82-7.

Alper KA, John ER, Brodie J, Gunther W, Daruwala R, Prichep LS.Correlation of PET and QEEG in normal Subjects. Psychiatry Research: Neuroimaging 2006; 146: 271-82.

John ER, Prichep LS. The Relevance of QEEG to the Evaluation of Behavioral Disorders and Pharmacological Interventions.Clinical EEG and Neuroscience 2006; 37: 135-43.

John ER, Prichep LS. Principles and applications of quantitative electroencephalogram in psychiatry. In: Sadock BJ, Sadock VA, Ruiz P, eds. Kaplan and Sadock¡¯s Comprehensive Textbook of Psychiatry. 9th edition. Philadelphia: Lippincott Williams & Wilkins; 2009: 1013-32.

Congedo M, John ER, De Ridder D, Prichep LS, Isenhart R. Group independent component analysis of resting-state EEG in large normative samples. International Journal of Psychophysiology 2010; 78(2): 88-99.

Congedo M, John ER, De Ridder D, Prichep LS, Isenhart R. On the ¡°Dependence¡± of ¡°Independent¡± Group EEG Sources; an EEG Study on Two Large Databases. Brain Topography 2010; 23(2):134-138.

- Source Localization

Prichep LS, John ER, Tom M. Localization of deep white matter lymphoma using VARETA ? A case study. Clinical EEG 2001; 32: 62-6.

Bosch-Bayard, J., Valdes-Sosa, P., Virues-Alba, E., Aubert-Vazquez, E., John, E. R., Harmony, T., Riera-Diaz, J., & Trujillo-Barreto, N. (2001). 3D Statistical Parametric Mapping of EEG Source Spectra by means of Variable Resolution Electromagnetic Tomography (VARETA).Clin EEG, 32, 47-61.

Alper K, Raghavan M, Isenhart R, Howard B, Doyle W, John ER, Prichep LS. Localizing epileptogenic regions in partial epilepsy using three-dimensional statistical parametric maps of background EEG source spectra.Neuroimage 2008; 39: 1257-65.

Pascual-Marqui RD, Lehmann D, Koukkou M, Kochi K, Anderer P, Saletu B, Tanaka H, Hirata K, John ER, Prichep LS, Biscay-Lirio R, Kinoshita T. Assessing interactions in the brain with exact low-resolution electromagnetic tomography. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 2011; 369: 3768-3784.


- Chemical Dependency

Alper KR, Prichep LS, Kowalik SC, Rosenthal MS. Persistent QEEG abnormality in crack cocaine users at 6 months of drug abstinence. Neuropsychopharm. 1998; 19: 1-9.

Prichep LS, Alper KR, Kowalik SC, Vaysblat L, Merkin HA, Tom M, John ER, Rosenthal MS. Prediction of treatment outcome in cocaine dependent males using quantitative EEG. Drug Alc.Depend. 1999; 54: 35-43.

Prichep LS, Alper KR, Sverdlov L, Kowalik SC, John ER, Merkin HTM, Howard B, Rosenthal MS. Outcome related electrophysiological subtypes of cocaine dependence. Clinical EEG 2002; 33: 8-20.

Reid MS, Prichep LS, Ciplet D, O¡¯Leary SO, Tom M, Howard B, Rotrosen J, John ER. Quantitative electroencephalographic studies of cue-induced cocaine craving. Clinical EEG 2003; 34: 1-14.

Reid MS, Flammino F, Howard B, Nilsen D, Prichep LS. Topographic imaging of Quantitative EEG in response to smoked cocaine self-administration in humans. Neuropsychopharmacology 2006; 31: 872-4.

Reid MS, Flammino F, Howard B, Nilsen D, Prichep LS. Cocaine cue versus cocaine dosing in humans: Evidence for distinct neurophysiological response profiles. Pharmacology Biochemistry and Behavior 2008; 91: 155-64.

Alper K, Shah J, Howard B, John ER, Prichep LS. Childhood abuse and EEG source localization in crack cocaine dependence. Psychiatry Research:Neuroimaging. 2013;213:63-70


- Cerebral Ischemia

Jonkman, E. J., Poortvliet, D. C. J., Veering, M. M., DeWeerd, A. W., & John, E. R. (1985). The use of neurometrics in the study of patients with cerebral ischemia. ElectroencephalogrClinNeurophysiol, 61, 333-341.

Veering, N. M., Jonkman, E. J., Poortvliet, D. C., de Weerd, A. W. , Tans, J. T., & John, E. R. (1986). The effect of reconstructive vascular surgery on clinical status, quantitative EEG and cerebral blood flow in patients with cerebral ischaemia. A three month follow-up study in operated and unoperated stroke patients. EEG ClinNeurophysiol, 64, 383-393.

John ER, Prichep LS, Chabot RJ, Isom WO. Monitoring brain function during cardiovascular surgery: Hypoperfusion vs. microembolism as the major cause of neurological damage during cardiopulmonary bypass. Heart and Brain, Brain and Heart. Heidelberg: Springer-Verlag; 1989.


- Learning Disabilities/ADHD/Child-Adolescent Psychiatry

Baird, H. W., John, E. R., Ahn, H., & and Maisel, E. (1980). Neurometric evaluation of epileptic children who do well and poorly in school. EEG ClinNeurophysiol, 48, 683-693.

Kaye H, John ER, Ahn H, Prichep LS.Neurometric evaluation of learning disabillities.Intl.J.Neurosci. 1981; 13: 15-25. John ER, Prichep LS, Fridman J, Ahn H, Kaye H, Baird H. Neurometric evaluation of brain electrical activity in children with learning disabilities. In: Duffy F, Geschwind N, eds. Dyslexia: A Neuroscientific Approach to Clinical Evaluation. Boston: Little, Brown & Co.; 1985: 157-85.

Lewis AL, Pincus JH, Bard B, Richardson E, Prichep LS, Feldman M, Yeager C. Neuropsychiatric, psychoeducational and family characteristics of 14 juveniles condemned to death in the U.S. Am J Psychiatry 1988; 145: 584-9.

John ER, Prichep LS, Ahn H, Kaye H, Brown D, Easton P, Karmel Z, Toro A, Thatcher R. Neurometric Evaluation of Brain Function in Normal and Learning Disabled Children. Ann Arbor, Univ. of Michigan Press; 1989.

Chabot RJ, Prichep LS, John ER.The clinical role of neurophysiology in child and adolescent psychiatry. In: Noshpitz JD, ed. Handbook of Child and Adolescent Psychiatry. 1996.

Chabot RJ, diMichele F, Prichep LS, John ER. The clinical role of computerized EEG in the evaluation and treatment of learning and attention disorders in children and adolescents. J Neuropsychiatry Clinical Neuroscience 2001; 13: 171-86.

di Michele F, Prichep LS, John ER, Chabot RJ. The neurophysiology of attention-deficit/hyperactivity disorder. International Journal of Psychophysiology 2005; 58: 81-93.

Chabot RJ, di Michele F, Prichep LS. The role of quantitative electroencephalography in child and adolescent psychiatric disorders.Child and Adolescent Psychiatric Clinics of North America 2005;14:21-53.

Chabot RJ, Orgill AA, Crawford G, Harris MJ, Serfontein G. Behavioral and Electrophysiological predictors of treatment response stimulants in children with attention disorders. J Child Neurology 1999;14:343-351.

Chabot RJ, Merkin H, Wood LM, Davenport TL, Serfontein G. Sensitivity and Specificity of QEEG in Children with Attention Deficit or Specific Developmental Learning Disorders.Clin EEG 1996;27:26-34.

Chabot RJ, Serfontein G. Quantitative EEG profiles of children with Attention Deficit Disorder. BiolPsychiat 1996;40:951-963.

Chabot RJ, Sigal LH. QEEG and evoked potentials in central nervous systemlyme disease. Clin EEG 1995;26:137-145.

Coben R, Chabot RJ, Hirshberg L. EEG Analyses in the Assessment of Autistic Disorders. In: Casanova MF, El-Baz AS, Suri JS, eds. Imaging the Brain in Autism. Springer New York; 2013;349-370.

Chabot RJ, Coben R, Hirshberg L, Cantor D.S. QEEG and VARETA based Neurophysiological Indices of Brain Dysfunction in Attention Deficit and Autustic Spectrum Disorder. Austin J Autism & Relat Disabil 2015; Volume 1 Issue 2.


- Consciousness and Mental Activity

John ER, Prichep LS, Katz J, Easton P, Chabot R. Topographic maps of EEGs coherence and EP factor structure at rest and during mental tasks. In: Takahashi R, Flor-Henry

J, Gruzelier J, Niwa S, eds. Cerebral Dynamics, Laterality and Psychopathology. Amsterdam: Elsevier; 1987.

John ER, Prichep LS, Chabot RJ. Quantitative Electrophysiological Maps of Mental Activity.Brain Dynamics 2 edn. 1989: 316-30.

John ER, Prichep LS, Chabot RJ. Quantitative electrophysiological maps of mental activity. In: Basar E, Bullock TH, eds. Dynamics of Sensory and Cognitive Processing by the Brain. Springer-Verlag; 1989.

Prichep LS, John ER, Easton P, Chabot R. Cross-spectral coherence at rest and during mental activity. In: John ER, ed. Machinery of the Mind. Boston: Birkhauser; 1990: 471-8.

John ER, Halper JP, Lowe RS3, Merkin H, DeFina P, Prichep LS. Source Imaging of QEEG as a bedside method to detect awareness in a patient in a vegetative state. Brain Injury 2011; 25[4], 426-432.


- Anesthesia ? Loss and Return of Consciousness

Prichep LS, John ER, Chabot RJ, Gugino LD, Kox W. PSI Prediction of ¡°arousal¡± events during surgery under continuous intravenous, inhalation or nitrous/narcotic anesthesia. Memory and Awareness in Anesthesia. Harrow: 1998.

Prichep LS, John ER, Gugino LD, Kox W, Chabot R. Quantitative EEG assessment of changes in the level of the sedation/hypnosis during surgery under general anesthesia: I. The Patient State Index (PSI). In: Jordan C, Vaughan DJA, Newton DEF, eds. Memory and Awareness in Anesthesia. IV edn. London: Imperial College Press; 2000: 97-102.

John ER, Prichep LS, Gugino LD, Kox W, Chabot RJ. Quantitative electroencephalographic (QEEG) changes accompanying loss and return of consciousness during inhalation anesthesia: II. Variable resolution electromagnetic tomography (VARETA).Memory and Awareness in Anesthesia IV. Northwick Park, Harrow, London: Imperial College Press; 2000: 102-7.

Gugino LD, Chabot RJ, Prichep LS, John ER, Formanek V, Aglio LS. Quantitative EEG changes associated with loss and return of consciousness in healthy adult volunteers anesthetized with propofol or sevoflurane. British J.Anaesth.2001; 87: 421-8.

John ER, Prichep LS, Kox W, Valdes-Sosa P, Bosch-Bayard J, Aubert E, Tom M, di Michele F, Gugino LD. Invariant reversible QEEG effects of anesthetics. Consciousness and Cognition 2001; 10: 165-83.

Drover D, Lemmens HJ, Pierce ET, Loyd G, Ornstein E, Prichep LS, Chabot RJ, Gugino L. Patient state index: titration of delivery and recovery from propofol, alfentanil, and nitrous oxide anesthesia. Anesthesiology 2002; 97: 82-9.

Prichep LS, Gugino LD, John ER, Chabot RJ, Howard B, Merkin HA, Tom M, Wolter S, Rausch L, Kox W. The Patient State Index (PSI) as an indicator of the level of hypnosis under general anesthesia. British Journal of Anaesthesia 2004; 92: 393-9.

Rundshagen I, Schroder T, Prichep LS, John ER, Kox WJ. Changes in cortical electrical activity during induction of anaesthesia with thiopental/fentanyl and tracheal intubation.A quantitative electroencephalographic analyses. British J.Anaesth.2004; 92: 33-8.

John ER, Prichep LS. The anesthetic cascade: how anesthesia suppresses awareness. Anesthesiology 2005; 102: 447-71. Kox W, von Heymann C, Heinze J, Prichep LS, John ER, Rundshagen I. Electroencephalographic mapping during routine clinical practice: cortical arousal during tracheal intubation? Anesthesia and Analgesia 2006; 102: 825-31.


- Adult Psychiatric Disorders and Neurological Disorders

Prichep LS, Mas F, Hollander E, Liebowitz M, John ER, Almas M, DeCaria CM, Levine RH. Quantitative electroencephalographic subtyping of obsessive-compulsive disorder. Psychiatry Res. 1993; 50 : 25-32.

Prichep LS, John ER, Alper K, Gomez-Mont F, Essig-Peppard T, Flitter M. Quantitative EEG in depressive disorders. In: Shagass C, Josiassen RC, and Roemer RA, eds. Brain Electrical Potentials and Psychopathology. Amsterdam: Elsevier; 1986: 223-44.

Prichep LS.Neurometric QEEG measures of depressive disorders. In: Takahashi P, Flor-Henry J, eds. Cerebral Dynamics, Laterality and Psychopathology. Amsterdam: Elsevier; 1987: 55-69.

Prichep LS, Mas F, John ER, Levine R. Neurometric subtyping of obsessive compulsive disorders. In: Stefanis CN, Rabavilas AD, Soldatos CR, eds. Psychiatry: A World Perspective. Amsterdam: Elsevier; 1990: 557-62.

Lieber AL, Prichep LS. Diagnosis and subtyping of depressive disorders by quantitative electroencephalography I: Discriminant analysis of selected variables in untreated depressives. The Hillside J of Clin.Psychiat.1988; 10: 71-83.

Prichep LS, John ER, Essig-Peppard T, Alper KR. Neurometric subtyping of depressive disorders. In: Cazzullo CL, Invernizzi G, Sacchetti E, Vita A, eds. Plasticity and Morphology of the CNS. London: M.T.P. Press; 1990.

Prichep LS, John ER, Mas F, Essig-Peppard T. Subtyping of Schizophrenia. In: John ER, ed. Machinery of the Mind. Birkhauser; 1990: 460-70.

Bolwig TG, Hansen ES, Hansen A, Merkin H, Prichep LS. Toward a better understanding of the pathophysiology of OCD SSRI responder: QEEG source localization. ActaPsychiatrScand 2007; 115: 237-42.

Prichep LS, John ER. QEEG profiles of psychiatric disorders. Brain Topography. 1992; 4: 249-257

Hansen ES, Prichep LS, Bolwig TG, John ER. Quantitative electroencephalography in OCD- patients treated with paroxetine. Clinical EEG 2003; 34: 70-4.

John ER, Prichep LS, Almas M. Subtyping of psychiatric patients by cluster analysis of QEEG.Brain Topogr. 1992; 4 : 321-326.

John ER, Prichep LS, Alper KR, Mas FG, Cancro R, Easton P, Sverdlov L. Quantitative electrophysiological characteristics and subtyping of schizophrenia. Biological Psychiatry 1994; 36: 801-26.

John ER, Prichep LS, Valdes-Sosa P. Neurometric EEG classification and subtyping of psychiatric disorders. EEG Clin.Neurophysiol. 1997; 103: 36.

Mas F, Prichep LS, John ER, Levine R. Neurometric QEEG subtyping of obsessive compulsive disorder. In: Maurer K, ed. Imaging of the Brain in Psychiatry and Related Fields. Berlin, Heidelberg: Springer-Verlag; 1993: 277-80.

Alper K, Gunther W, Prichep LS, John ER, Brodie J. Correlation of QEEG with PET in Schizophrenia.Neuropsychobiology 1998; 38: 50-6.

Brasic JR, Zagzag D, Kowalik S, Prichep LS, John ER, Barmett JY, Bronson B, Nadrich RH, Cancro R, Buchsbaum M, Brathwaite C. Clinical Manifestations of Progressive Catatonia.German Journal of Psychiatry 2000; 3: 24.

John ER, Prichep LS, Winterer G, Hermann WM, diMichele F, Halper J, Bolwig T, Cancro R. Electrophysiological subtypes of psychotic states. ActaPsychiatrica Scandinavia 2007; 116: 17-35.

Prichep LS, John ER, Howard B, Merkin H, Hiesiger E. Assessment of pain using Quantitative EEG source imaging. Pain Medicine.2011; 12: 1241-48.

Prichep LS, John ER, Howard B, Merkin H, Hiesiger E. Evaluation of the pain matrix using EEG source localization: a feasibility study. Pain Medicine 2011;12:1241-1248.

Chabot RJ, Sigal LH. QEEG and evoked potentials in central nervous system lyme disease. Clin EEG 1995;26:137-145.


- Aging and Dementia

Prichep LS, Gomez-Mont F, John ER, Ferris SH. Neurometric Electroencephalographic characteristics of dementia. In: Reisberg B, ed. Alzheimer¡¯s Disease: The Standard Reference. The Free Press (MacMillan); 1983: 252-7.

John ER, Prichep LS. Neurometric studies of aging and cognitive impairment. In: Uylings HBM, Van Eden CGV, De Bruin JPC, Corner MA, Feenstra MGP, eds. The Prefrontal Cortex. Progress in Brain Research. Amsterdam: Elsevier; 1990: 545-55.

Prichep LS, John ER, Ferris SH, Reisberg B, Alper KR, Cancro R. Quantitative EEG correlates of cognitive deterioration in the elderly. Neurobiology Aging 1994; 15: 85-90.

Koenig T, Prichep LS, Dierks T, Hubl D, Wahlund LO, John ER, Jelic V. Decreased EEG synchronization in Alzheimer¡¯s disease and mild cognitive impairment. Neurobiology of Aging 2005; 26: 165-71.

Prichep LS, John ER, Ferris SH, Rausch L, Fang Z, Rausch L, Cancro R, Torrossian C, Reisberg B. Prediction of longitudinal cognitive decline in normal elderly with subjective complaints using electrophysiological imaging. NeuroBiol Aging 2006; 27: 471-81.

Prichep LS.Quantitative EEG and Electromagnetic Brain Imaging in Aging and in the Evolution of Dementia.Ann.N.Y.Acad Sci. 2007; 40: 1-12.

Lehmann C, Koenig T, Jelic V, Prichep LS, John ER, Walhlund L, Dodge Y, Dierks T. Application and comparison of classification algorithms for recognition of Alzheimer¡¯s disease in electrical brain activity (EEG). Journal of Neuroscience Methods 2007; 161: 342-50.

Reisberg B, Prichep LS, Mosconi L, John ER, Glodzik-Sobanska L, Boksay I, Monteiro I, Torossian C, Vedvyas A, Ashraf N, Jamil IA, de Leon MJ. The pre-mild cognitive impairment, subjective cognitive impairment stage of Alzheimer¡¯s disease. Alzheimer¡¯s and Dementia 2008; 4: S98-S108.


- Treatment Applications

Cantor, D.S. An Overview of Quantitative EEG and Its Applications to Neurofeedback. In J. Evans (Ed.) Introduction to Neurofeedback.

New York: Academic Press, 1999.

Cantor, D.S. & Stevens, E. QEEG Correlates to Auditory-Visual Entrainment In Refractory Depression ? Journal of Neurotherapy, 13,100-108, 2009

Cantor,D. Applying advanced methods in clinical practice. In Budzynski, T, Budzynski, H., Evans, J. and Abarbanel, A. Introduction to Quantitative EEG and Neurofeedback: Advance Theory and Applications, 2nd Ed. Academic Press, 2009, 63-81.

Cantor, D. & Evans, J. (Eds.) Clinical Methods of Neurotherapy: Techniques and Treatment Applications. Elsevier Press, In press, 2013.


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